Roches alzheimerprogram vidare till fas III efter positiva data

Roche rapporterar positiva preliminära data från sitt alzheimerprojekt trontinemab, och ska nu gå vidare med en fas III-studie.

By Anders Göransson

April 4, 2025 11:40 AM

Tidiga data från en fas Ib/IIa-studie med 114 deltagare tyder, enligt ett pressmeddelande från det schweiziska läkemedelsbolaget, på ”en snabb och djup, dosberoende minskning av amyloidplack i hjärnan”.

De två hittills USA-godkända bromsläkemedlen för Alzheimers sjukdom, lecanemab och donanemab, är inriktade på just beta-amyloid-plack som bildats i hjärnan.

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